Circulating miR-499 as a potential biomarker for acute myocardial infarction
نویسندگان
چکیده
منابع مشابه
Circulating miR-122-5p as a potential novel biomarker for diagnosis of acute myocardial infarction.
BACKGROUND MicroRNAs (miRNAs) play key roles in cardiac development, and the expression of miRNAs is altered in the diseased heart. The aim of this study was to explore the value of circulating microRNA-122-5p (miR-122-5p) as a potential biomarker for acute myocardial infarction (AMI). METHODS Plasma samples from 50 patients with AMI and 39 healthy adults (non-AMI controls) were collected. Th...
متن کاملCirculating miR-181a as a Potential Novel Biomarker for Diagnosis of Acute Myocardial Infarction.
BACKGROUND In this study, we tested the hypothesis that miR-181a levels increase during acute myocardial infarction. We investigated circulating miR-181a as a potential novel biomarker for early diagnosis of acute myocardial infarction (AMI). METHODS From June 2014 to June 2016, 120 consecutive eligible patients with AMI (n = 60) or unstable angina (UA; n = 60) and 60 control subjects were en...
متن کاملCirculating miR-379 as a potential novel biomarker for diagnosis of acute myocardial infarction.
OBJECTIVE Previous studies have demonstrated that microRNA-379 (miR-379) was involved in regulating cell proliferation. The present study aimed to investigate its potential role in the diagnosis of cute myocardium infarction (AMI). PATIENTS AND METHODS Plasma samples from 30 patients with AMI and 30 healthy adults (non-AMI controls) were collected. The abundance of circulating miR-379 was det...
متن کاملPlasma microRNA 499 as a biomarker of acute myocardial infarction.
BACKGROUND MicroRNAs (miRNAs) are endogenous small RNAs 21-25 nucleotides in length. Recently, we reported that miRNA 208 (miR-208) is produced exclusively in the rat myocardium and that plasma miR-208 is a biomarker of myocardial injury in rats. In the present study, we assessed the hypothesis that plasma concentrations of myocardial-specific miRNAs can be used to diagnose myocardial injury in...
متن کاملCirculating microRNA-19a as a Potential Novel Biomarker for Diagnosis of Acute Myocardial Infarction
Acute myocardial infarction (AMI) is a serious cardiovascular disease. Investigating new susceptibility genes for effective methods of early diagnosis of AMI is important. In the current study, peripheral blood miR-19a levels were detected by real-time polymerase chain reaction. Significant differences and logistic correlation analyses were carried out by grouping of disease types and stratific...
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ژورنال
عنوان ژورنال: Annals of Translational Medicine
سال: 2016
ISSN: 2305-5839,2305-5847
DOI: 10.21037/atm.2016.03.40