Clinical characteristics of thrombospondin type-1 domain-containing 7A-associated membranous nephropathy
نویسندگان
چکیده
منابع مشابه
Prevalence of Enhanced Granular Expression of Thrombospondin Type-1 Domain-Containing 7A in the Glomeruli of Japanese Patients with Idiopathic Membranous Nephropathy
Membranous nephropathy (MN) is a leading cause of nephrotic syndrome in adults. Autoantibodies against M-type phospholipase A2 receptor (PLA2R) and thrombospondin type-1 domain-containing 7A (THSD7A), which mainly belong to the IgG4 subclass, were reported as associated antibodies for the development of MN. Although PLA2R is a major target antigen for idiopathic MN, the prevalence of MN patient...
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Preeclampsia, a relatively common pregnancy disorder, is a major contributor to maternal mortality and morbidity worldwide. An elevation in microRNA-210 (miR-210) expression in the placenta has been reported to be associated with preeclampsia. Our bioinformatic analysis showed that thrombospondin type I domain containing 7A (THSD7A) is a predicted target for miR-210. The aim of this study was t...
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The concurrent antineutrophil cytoplasmic antibody-associated glomerulonephritis (ANCA-GN) and membranous nephropathy (MN) have been increasingly documented, mainly in case studies and case series; however, the differences of clinical and pathologic characteristics as well as outcomes between ANCA-GN patients with and without MN remain unclear. The current study investigated the clinical and im...
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Membranous nephropathy (MN) is one of the most common biopsy diagnoses in adults, and it has been associated with chronic infections, autoimmune diseases, malignancies, and drugs. However, MN associated with cholesterol crystal emboli has never been reported. Here we present a patient with MN as an unusual manifestation of atheroembolism. A 75-year-old man with worsening renal function after ca...
متن کاملMembranous Nephropathy Associated with Tuberculosis
Correspondence To the Editor: Glomerulonephritis (GN) due to Mycobacterium tuberculosis (M. tuberculosis) is rare, [1] and membranous nephropathy (MN) associated with tuberculosis is seldom reported. Because of atypical and nonspecific manifestations, tuberculosis‑associated GN (TB‑GN) is difficult to diagnose. Patients usually present with hematuria, proteinuria, edema, and varying degrees of ...
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ژورنال
عنوان ژورنال: Renal Failure
سال: 2020
ISSN: 0886-022X,1525-6049
DOI: 10.1080/0886022x.2020.1819318