Clinical presentation and diagnosis of multiple sclerosis

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hla profile and clinical presentation of multiple sclerosis in iran

multiple sclerosis (ms) is a demyelinating disease of the central nervous system,with unknown etiology in which both genetic and environmental factors are thought to be involved. the hla system provides a set of genetic markers which lend themselves to systematic study. the disease also has variable clinical manifestations, ranging from a relapsing-remitting course to a chronic progressive dise...

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hla profile and clinical presentation of multiple sclerosis in iran

multiple sclerosis (ms) is a demyelinating disease of the central nervous system, with unknown etiology in which both genetic and environmental factors are thought to be involved. the human leukocyte antigen (hla) system provides a set of genetic markers which lend themselves to systematic study. in iran, hla-a24, hla-dr2, and hla- dr15 are significantly increased in ms patients. the disease al...

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Clinical Pearl The Diagnosis of Multiple Sclerosis

Introduction Multiple sclerosis (MS) is a relatively common disorder affecting between 250 000 to 350 000 people in the US alone [1, 2]. The age of onset is typically between 20 to 40 years of age with a 2:1 predominance of females over males [2]. Although the exact etiology remains unknown, current data suggest both genetic and environmental influences [3]. The underlying pathophysiology of MS...

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Hla Profile and Clinical Presentation of Multiple Sclerosis in Iran

Multiple sclerosis (MS) is a demyelinating disease of the central nervous system, with unknown etiology in which both genetic and environmental factors are thought to be involved. The human leukocyte antigen (HLA) system provides a set of genetic markers which lend themselves to systematic study. In Iran, HLA-A24, HLA-DR2, and HLADR15 are significantly increased in MS patients. The disease also...

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White Matter Diseases YES, Multiple Sclerosis NO, Sjogren - Larsson Syndrome: Another Differential Diagnosis of Multiple Sclerosis

Sjogren-Larsson Syndrome (SLS) is an inherited autosomal recessive neurocutaneous disorder with congenital ichthyosis, spastic diplegia or quadriplegia and mental retardation. We report a case of Sjogren-Larsson Syndrome with clinical profile (mental retardation, ichthyosis, spastic diplegia) and MRI findings such as seen in multiple sclerosis (MS). So this rare syndrome can be another differen...

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ژورنال

عنوان ژورنال: Clinical Medicine

سال: 2020

ISSN: 1470-2118,1473-4893

DOI: 10.7861/clinmed.2020-0292