Clinical trial design for invasive aspergillosis: time to cast a different mold
نویسندگان
چکیده
منابع مشابه
Clinical risk factors for invasive aspergillosis.
Despite improvements in the antifungal armamentarium and diagnostic modalities, invasive aspergillosis (IA) remains an important cause of morbidity and mortality in immunocompromised patients. There is an emergence of non-traditional groups at risk for IA, including intensive care unit (ICU) patients, post-operative patients, those with chronic pulmonary diseases, patients with AIDS and patient...
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BACKGROUND Invasive aspergillosis (IA) is associated with poor outcomes in patients with hematologic malignancies (HMs) and hematopoietic cell transplantation (HCT). Small studies suggest a role for combination antifungal therapy. OBJECTIVE To assess the safety and efficacy of voriconazole and anidulafungin compared with voriconazole monotherapy for treatment of IA. DESIGN Randomized, doubl...
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This book is authored by a group of individuals who have published several important papers in the area of injection mold design and are quite knowledgeable in the field. They belong to a select group of academicians who have successfully commercialized the software developed in their laboratory. Overall, I found this book to be easy to read and full of useful information. This book should be a...
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Background and purpose: COVID-19 is an emerging viral disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Bacterial or fungal superinfections of the lung may cause complications in clinical manifestations, treatment, and increase the mortality rate. In this article, we reviewed previous studies on invasive aspergillosis (IA) in viral infections and in adjustment with...
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Monitoring the response to therapy for invasive aspergillosis (IA) is essential for the management of patients with hematologic diseases. We evaluated the correlation between the outcome of real-time nucleic acid sequence-based amplification (RTi-NASBA) for Aspergillus 18S rRNA and the clinical outcome of IA. A total of 157 serum samples from 29 patients with IA were tested for RTi-NASBA. The t...
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ژورنال
عنوان ژورنال: Medical Mycology
سال: 2009
ISSN: 1369-3786,1460-2709
DOI: 10.1080/13693780902718057