منابع مشابه
Evaluation of Clinical Trials
In a number of important clinical issues such as evaluation of the efficacy or effectiveness of therapeutic or preventive interventions as well as for comparing the harms of interventions, randomized controlled trials (RCTs) provide the highest levels of evidence, either directly or indirectly. It is obvious that critical appraisal of these studies to assess their validity and precision is of p...
متن کاملClinical trials: new opportunities.
Human cognitive aging has been too long neglected and underappreciated for its critical importance to quality of life in old age. The articles in this session present novel approaches to improving cognitive function in normal aging persons with drugs and interventions that are based on findings in epidemiology, studies in aged animals, and in vitro research. In addition, since aging is the prim...
متن کاملEvidence Based Medicine: Clinical Trials
Evidence based medicine is very important for success of modern medicine. It is the ongoing process of using the most reliable evidence from clinical studies, scientific understanding and medical practice to make the best possible medical choice for patients. Evidence based medicine is how medicine advances and how we get improvements in life expectancy and quality of life. It not only identifi...
متن کاملSome Recent Developments in the Design of Adaptive Clinical Trials
For clinical trials that compare two or more competing treatments, the literature proposes several randomization rules that aim at favouring, at each stage of the trial, the treatment that appears to be best. In two recent papers the present authors have suggested criteria of optimal allocation that combine inferential precision and ethical gain by means of flexible weights, in order to achieve...
متن کاملANCA Diagnostics in Clinical Practice: New Developments
Anti-neutrophil cytoplasmic antibodies (ANCA) are the hallmark of the so-called ANCAassociated vasculitides (AAV) (Jennette & Falk, 1997). These primary small-vessel vasculitides comprise granulomatosis with polyangiitis (GPA, previously referred to as Wegener’s granulomatosis) (Falk et al, 2011), the Churg-Straus syndrome (CSS), microscopic polyangiitis (MPA), and renal-limited necrotizing cre...
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ژورنال
عنوان ژورنال: Canadian Respiratory Journal
سال: 2000
ISSN: 1198-2241
DOI: 10.1155/2000/195837