CLIP and complementary methods

Computational Methods for CLIP-seq Data Processing

RNA-binding proteins (RBPs) are at the core of post-transcriptional regulation and thus of gene expression control at the RNA level. One of the principal challenges in the field of gene expression regulation is to understand RBPs mechanism of action. As a result of recent evolution of experimental techniques, it is now possible to obtain the RNA regions recognized by RBPs on a transcriptome-wid...

When are methods complementary?

We address the issue of when software development methods are complementary, i.e., determining when a method is capable of a task that another method cannot perform. Our intent is to examine complementarity in order to help determine when to carry out method integration. We propose some factors for method complementarity, and suggest that contextdependent criteria, such as real-world domain and...

Two way street – complementary methods

Complementary and alternative methods in cerebral palsy.

There are no published studies specifically addressing complementary and alternative treatments in adults with cerebral palsy (CP). However, national surveys of adults with chronic disabilities document that a majority of them use such treatments, that they are willing to pay out of pocket, if necessary, and that they believe that pursuing such treatment relieves pain, reduces stress and anxiet...

Complementary Rather Than Competitive Methods

Clinic (office) blood pressure (BP) measurement has a well-established role in medical practice and is the standard on which most of the literature is based. However, clinic BP has several important limitations, including the potential for inadequate or misleading estimates of a patient’s true BP status and suboptimal prediction of cardiovascular risk. Particularly relevant is the concern that ...