Closed-loop insulin delivery system enhances type 1 diabetes glycemic control
نویسندگان
چکیده
منابع مشابه
Closed-loop insulin delivery for treatment of type 1 diabetes
Type 1 diabetes is one of the most common endocrine problems in childhood and adolescence, and remains a serious chronic disorder with increased morbidity and mortality, and reduced quality of life. Technological innovations positively affect the management of type 1 diabetes. Closed-loop insulin delivery (artificial pancreas) is a recent medical innovation, aiming to reduce the risk of hypogly...
متن کاملA Review of Closed-Loop Algorithms for Glycemic Control in the Treatment of Type 1 Diabetes
With the discovery of insulin came a deeper understanding of therapeutic options for one of the most devastating chronic diseases of the modern era, diabetes mellitus. The use of insulin in the treatment of diabetes, especially in those with severe insulin deficiency (type 1 diabetes), with multiple injections or continuous subcutaneous infusion, has been largely successful, but the risk for sh...
متن کاملSimulation environment to evaluate closed-loop insulin delivery systems in type 1 diabetes.
BACKGROUND Closed-loop insulin delivery systems linking subcutaneous insulin infusion to real-time continuous glucose monitoring need to be evaluated in humans, but progress can be accelerated with the use of in silico testing. We present a simulation environment designed to support the development and testing of closed-loop insulin delivery systems in type 1 diabetes mellitus (T1DM). METHODS...
متن کاملClosed-Loop Insulin Delivery During Pregnancy Complicated by Type 1 Diabetes
OBJECTIVE This study evaluated closed-loop insulin delivery with a model predictive control (MPC) algorithm during early (12-16 weeks) and late gestation (28-32 weeks) in pregnant women with type 1 diabetes. RESEARCH DESIGN AND METHODS Ten women with type 1 diabetes (age 31 years, diabetes duration 19 years, BMI 24.1 kg/m(2), booking A1C 6.9%) were studied over 24 h during early (14.8 weeks) ...
متن کاملClosed-Loop Basal Insulin Delivery Over 36 Hours in AdolescentsWith Type 1 Diabetes Randomized clinical trial
RESEARCH DESIGN AND METHODSdTwelve adolescents with type 1 diabetes (five males; mean age 15.0 [SD 1.4] years; HbA1c 7.9 [0.7]%; BMI 21.4 [2.6] kg/m ) were studied at a clinical research facility on two occasions and received, in random order, either closed-loop basal insulin delivery or conventional pump therapy for 36 h. During closed-loop insulin delivery, pump basal rates were adjusted ever...
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ژورنال
عنوان ژورنال: The Journal of Pediatrics
سال: 2020
ISSN: 0022-3476
DOI: 10.1016/j.jpeds.2019.12.050