Cocaine Modulates the Expression of Opioid Receptors and miR-let-7d in Zebrafish Embryos

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Cocaine Modulates the Expression of Opioid Receptors and miR-let-7d in Zebrafish Embryos

Prenatal exposure to cocaine, in mammals, has been shown to interfere with the expression of opioid receptors, which can have repercussions in its activity. Likewise, microRNAs, such as let-7, have been shown to regulate the expression of opioid receptors and hence their functions in mammals and in vitro experiments. In light of this, using the zebrafish embryos as a model our aim here was to e...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2012

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0050885