Codon usage and bias in mitochondrial genomes of parasitic platyhelminthes

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Codon usage and bias in mitochondrial genomes of parasitic platyhelminthes.

Sequences of the complete protein-coding portions of the mitochondrial (mt) genome were analysed for 6 species of cestodes (including hydatid tapeworms and the pork tapeworm) and 5 species of trematodes (blood flukes and liver- and lung-flukes). A near-complete sequence was also available for an additional trematode (the blood fluke Schistosoma malayensis). All of these parasites belong to a la...

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Synonymous codon usage patterns in different parasitic platyhelminth mitochondrial genomes.

We analyzed synonymous codon usage patterns of the mitochondrial genomes of 43 parasitic platyhelminth species. The relative synonymous codon usage, the effective number of codons (NC) and the frequency of G+C at the third synonymously variable coding position were calculated. Correspondence analysis was used to determine the major variation trends shaping the codon usage patterns. Among the mi...

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Factors Influencing Codon Usage Bias in Genomes

O código genético é degenerado, isto é, o mesmo amino ácido pode ser codificado por vários codons. Apesar de codificarem o mesmo amino ácido, estes codons sinônimos não são utilizados da mesma forma em genomas diferentes, e mesmo em um único genoma o padrão de uso dos codons sinônimos pode variar muito entre os genes, ou ainda ao longo de um único gene. Com a recente introdução de seqüências ge...

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Mutation and Selection Cause Codon Usage and Bias in Mitochondrial Genomes of Ribbon Worms (Nemertea)

The phenomenon of codon usage bias is known to exist in many genomes and it is mainly determined by mutation and selection. To understand the patterns of codon usage in nemertean mitochondrial genomes, we use bioinformatic approaches to analyze the protein-coding sequences of eight nemertean species. Neutrality analysis did not find a significant correlation between GC12 and GC3. ENc-plot showe...

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Comparative Analysis of Codon Usage Bias Patterns in Microsporidian Genomes

The sub-3 Mbp genomes from microsporidian species of the Encephalitozoon genus are the smallest known among eukaryotes and paragons of genomic reduction and compaction in parasites. However, their diminutive stature is not characteristic of all Microsporidia, whose genome sizes vary by an order of magnitude. This large variability suggests that different evolutionary forces are applied on the g...

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ژورنال

عنوان ژورنال: The Korean Journal of Parasitology

سال: 2004

ISSN: 0023-4001

DOI: 10.3347/kjp.2004.42.4.159