Combination of Dacarbazine and Dimethylfumarate Efficiently Reduces Melanoma Lymph Node Metastasis
نویسندگان
چکیده
منابع مشابه
Dimethylfumarate impairs melanoma growth and metastasis.
Dimethylfumarate (DMF) inhibits signals transmitted by Rel proteins and is used for the treatment of inflammatory skin diseases such as psoriasis, but potential effects of DMF on tumor progression have yet not been analyzed. We show that DMF reduced melanoma growth and metastasis in severe combined immunodeficient mouse models. To identify targets of DMF action, we analyzed mRNA expression in D...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2010
ISSN: 0022-202X
DOI: 10.1038/jid.2009.368