Combined Hepatocellular and Cholangiocarcinoma: a Clinicopathologic Study of 26 Resected Cases
نویسندگان
چکیده
منابع مشابه
Clinicopathologic Study on Combined Hepatocellular Carcinoma and Cholangiocarcinoma: with Emphasis on the Intermediate Cell Morphology
Combined hepatocellular carcinoma and cholangiocarcinoma (combined HCC-CC) is a rare subtype of primary liver cancer. We investigated the histopathologic features of transitional or intermediate areas in 21 combined HCC-CCs and immunophenotypes using different hepatic progenitor cell markers (CK7, CK19, c-kit, NCAM, and EpCAM). Major histologic findings of transitional or intermediate areas of ...
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Combined hepatocellular and cholangiocarcinoma with sarcomatous transformation was first recognized in Ramathibodi Hospital in 2005. This variant of carcinoma has been increasingly reported particularly from Asian countries. Dedifferentiation of the epithelial component to various sarcomatous components is likely the underlying mechanism. The causative factors of hepatocarcinogenesis in Thailan...
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Combined hepatocellular carcinoma and cholangiocarcinoma (combined HCC-CC) is a rare subtype of liver cancer displaying components of both hepatocellular and cholangiocellular carcinoma. Not only are exophytic liver tumors very rare, but their diagnosis presents a challenge due to the uncertainty of the tumor origin. In this issue, we present a case of exophytic combined HCC-CC with unusual mor...
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The reported frequency of combined hepatocellular and cholangiocarcinoma (combined tumors) varies widely; 1.0-6.5% among patients with primary liver cancer. Statistical data indicate that combined tumors occur predominantly in men (reported ratio is ranged from 14:1 to 2:1). The mean age of onset is in the sixth decade. In Asian cases, a high incidence of hepatitis B or C virus infection and fr...
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Combined hepatocellular-cholangiocarcinoma is a rare but unique primary hepatic tumor with characteristic histology and tumor biology. Recent development in genetics and molecular biology support the fact that combined hepatocellular-cholangiocarcinoma is closely linked with cholangiocarcinoma, rather than hepatocellular carcinoma. Combined hepatocellular cholangiocarcinoma tends to present wit...
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ژورنال
عنوان ژورنال: Japanese Journal of Clinical Oncology
سال: 2003
ISSN: 1465-3621
DOI: 10.1093/jjco/hyg056