Comment on: Short pulse width widens the therapeutic window of subthalamic neurostimulation
نویسندگان
چکیده
منابع مشابه
Short pulse width widens the therapeutic window of subthalamic neurostimulation
We explored the impact of pulse durations <60 μsec on the therapeutic window of subthalamic neurostimulation in Parkinson's disease. Current thresholds for full rigidity control and first muscle contractions were evaluated at pulse durations between 20 and 120 μsec during a monopolar review session in four patients. The average therapeutic window was 2.16 mA at 60 μsec, which proportionally inc...
متن کاملComment on: Short pulse width widens the therapeutic window of subthalamic neurostimulation
We wish to comment on the assertion that a “short pulse width widens the therapeutic window of subthalamic neurostimulation,” as reported by Reich et al. In that publication, the authors defined “therapeutic window” in deep brain stimulation as the difference in current between the onset of full rigidity control and the onset of adverse muscle contractions at a given pulse duration. They determ...
متن کاملReply to comment on: Short pulse width widens the therapeutic window of subthalamic neurostimulation
We have read with interest the comment of McDermott et al. on our article “Short pulse width widens the therapeutic window of subthalamic neurostimulation”. While the authors provide an elegant and sophisticated argument trying to prove our data wrong, they disregard a simple rule of experimentation from the viewpoint of theoretical biophysics: Deep brain stimulation systems do not have a “char...
متن کاملSubthalamic neurostimulation for Parkinson ’ s disease
Electrical stimulation of the subthalamic nucleus is an established treatment for patients with advanced Parkinson’s disease with pharmacologically un responsive fl uctuations. Compared with pharmacological treatment, subthalamic neurostimulation signifi cantly improves motor symptoms, particularly during the phases of poor response to drug treatment, and reduces the severity of dyskinesias. Im...
متن کاملTherapeutic Neurostimulation and Schizophrenia
Electroconvulsive therapy Schizophrenia and schizoaffective disorder are indications for use of ECT, according to the FDA executive summary for the Neurological Devices Panel Meeting.1 In the US, ECT is predominantly used in the treatment of mood disorders, whereas in Asian countries, it is commonly used in the treatment of schizophrenia despite the relatively modest evidence for efficacy. Rand...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of Clinical and Translational Neurology
سال: 2015
ISSN: 2328-9503,2328-9503
DOI: 10.1002/acn3.253