Commentary: How to predict disaster?

How to Predict Congruential Generators

In this paper we show how to predict a large class of pseudorandom number generators. We consider congruential generators which output a sequence of integers k SO.Sl,... where si is computed by the recurrence si r I: ai @j(so,sl,...Si_l) (mod ml for j=l integers m and Ctj , and integer functions @j , j=l,...,k. Our predictors are @cient, provided that the jimctions Oj are computable (over the i...

MicroRNA Targets - How to predict?

A number of web tools are available for the prediction and identification of target microRNAs (miRNAs). The choice, availability, validity and selection of an optimal yet appropriate tool are a challenge for the design of high throughput assays with promising miRNA targets. The current trends and challenges for target microRNAs (miRNAs) prediction, identification and selection is described in t...

The following commentary is an appendix to the Commentary: Disaster Preparedness and Pediatrics: What’s Next? The Youngest Victims: Disaster Preparedness to Meet Children’s Needs

How to Predict Molecular Interactions between Species?

Organisms constantly interact with other species through physical contact which leads to changes on the molecular level, for example the transcriptome. These changes can be monitored for all genes, with the help of high-throughput experiments such as RNA-seq or microarrays. The adaptation of the gene expression to environmental changes within cells is mediated through complex gene regulatory ne...

How to predict and diagnose postthrombotic syndrome.

Postthrombotic syndrome (PTS) is the most frequent complication of deep vein thrombosis (DVT). From 20% to 50% of the patients will develop PTS after DVT, and from 5% to 10%, severe PTS. PTS is diagnosed on clinical grounds, based on the presence of signs and symptoms of venous insufficiency in the leg ipsilateral to DVT. The Villalta scale, a clinical scale that incorporates venous symptoms an...