Common precursor to corticotropins and endorphins
نویسندگان
چکیده
منابع مشابه
Acquired resistance to corticotropins.
Corticotropin, which may be defined as a pituitary extract that will directly stimulate the adrenal cortex to secrete its predominantly "glucocorticoid" hormones, has been in general use for about 5 years. In spite of this, its use as a therapeutic agent has not been defined. There are two reasons for this state of affairs. The first is that most physicians have assumed that the administration ...
متن کاملCorticotropins (acth)
Purified alpha-corticotropin has been reported to exercise the following biological effects: (a) stimulation of the adrenal glands in normal and hypophysectomized rats, (b) production of blood eosinopenia in hypophysectomized rats, (c) maintenance of muscle glycogen in hypophysectomized rats, (d) inhibition of growth-promoting activity of somatotropin, (e) stimulation of melanocytes in the skin...
متن کاملEndorphins, dopamine, and schizophrenia.
The theory that alterations of dopaminergic synaptic transmission may play a role in the pathogenesis of schizophrenia is widely accepted. A more recent theory links the endorphin system to the etiology of schizophrenia. We propose that these two theories may be combined into a single model. Recent neurochemical and pharmacological findings have indicated close functional relationships between ...
متن کاملAcupuncture and endorphins.
Acupuncture and electroacupuncture (EA) as complementary and alternative medicine have been accepted worldwide mainly for the treatment of acute and chronic pain. Studies on the mechanisms of action have revealed that endogenous opioid peptides in the central nervous system play an essential role in mediating the analgesic effect of EA. Further studies have shown that different kinds of neurope...
متن کاملEndorphins and psychiatry.
The term 'endorphin' (a combination of endogenous-morphine) is used to designate the entire group of peptides found in the brain and pituitary that mimic the biological properties of opiates. 'Endogenous opioid peptides', 'endogenous opioids' 'opioid peptide' and 'endopioids' can be considered as synonymous. Since the identification of stereospecific opiate receptors2J and the pentapeptides met...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1977
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.74.7.3014