Comparative study between intravenous anesthesia (propofol) and inhalational anesthesia (sevoflurane) on the cytokine’s response to abdominal operation

Introduction These days, the need for more information and familiarity with inflammatory response to different anesthetic drugs increase. Not only some patients suffering from immune reactions against drugs, but all surgical are liable decrease in immunity postoperatively. This may increase postoperative morbidity mortality, affects healing, spread of tumors is due surgery trauma causing imbalance cytokine response. Patients methods article was written on 40 patients, were randomly classified into four equal classes. Class A: inhalational anesthesia major operation. B: intravenous C: minor D: Results The authors found that proinflammatory [interleukin (IL)-6] levels postoperatively classes higher than operation Anti-inflammatory (IL-10) increases slightly anesthesia, especially after 24 h postoperatively, We also noticed a correlation between cortisol level IL-6 levels, this means an which shows slight level. Conclusion Inhalational had highest effect induce operations whether or