Comparative study of PAP smear and colposcopy with cervical biopsy

Background: Cervical Cancer is the second most common cancer among women worldwide approximately 80% of which occurred in developing countries. Out all cervical cases seen world, only 14% are developed countries, while about 86% occurs The leading cause Indian women. usually preceded by a long phase cytological changes, known as intraepithelial neoplastic (CIN) and takes period 15-20 years before invasive develops". Thus can be prevented if cellular changes detected treated early stage. World Health organization considers preventable disease. This because it diagnosed its precancerous phase. So we have done study to efficacy pap smear colposcopy. Comparative PAP colposcopy with biopsy symptomatic/ unhealthy cervix. Methods: All high risk reproductive, perimenopausal postmenopausal age group who presented cervix on naked eye examination, abnormal vaginal discharge, post coital bleeding, intermenstrual spotting/bleeding, that bleeds touch uterine bleeding. An informed consent was obtained performing Pap's In case there cytology report, patient's done. Results: sensitivity Pap 50%, specificity 86.6%, positive predictive value (PPV) 37.8%, negative 91.4%. coloposcopy 96.4, 39.53 20.61%, 98.55%. Conclusions: Colposcopy definitely more sensitive accurate than smear. By combining colposcopy, maximize screening.