Comparison of characteristics of Q beta replicase-amplified assay with competitive PCR assay for Chlamydia trachomatis

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Novel, ultrasensitive, Q-beta replicase-amplified hybridization assay for detection of Chlamydia trachomatis.

A sensitive, nonisotopic hybridization assay termed "dual capture" is described. The assay rapidly and specifically detects very low levels of target nucleic acids and organisms. The assay is based on the principles of sandwich hybridization, reversible target capture, and Q-Beta replicase amplification. The assay can be completed in less than 4 h, and in the described model format, it detects ...

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ژورنال

عنوان ژورنال: Journal of Clinical Microbiology

سال: 1995

ISSN: 0095-1137,1098-660X

DOI: 10.1128/jcm.33.1.58-63.1995