Comparison of transcriptional profiles of interferons, CXCL10 and RIG-1 in influenza infected A549 cells stimulated with exogenous interferons
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چکیده
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چکیده ندارد.
15 صفحه اولInterferons
nterferons, naturally occuring glycoproteins with molecular weights of approximately 20,000 daltons, possess antiviral, antiproliferative, and immune-stimulating properties. They are classified into 3 antigenically distinct forms that are derived from different cell types. Alpha (or) interferons are derived from leukocytes, beta ([3) interferons from fibroblasts, and gamma (/) interferons from ...
متن کاملType I and Type III Interferons Drive Redundant Amplification Loops to Induce a Transcriptional Signature in Influenza-Infected Airway Epithelia
Interferons (IFNs) are a group of cytokines with a well-established antiviral function. They can be induced by viral infection, are secreted and bind to specific receptors on the same or neighbouring cells to activate the expression of hundreds of IFN stimulated genes (ISGs) with antiviral function. Type I IFN has been known for more than half a century. However, more recently, type III IFN (IF...
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ژورنال
عنوان ژورنال: Acta virologica
سال: 2017
ISSN: 1336-2305
DOI: 10.4149/av_2017_02_07