Comparison of two purified toxic fractions from Mesobuthus eupeus scorpion venom

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Comparison of two purified toxic fractions from Mesobuthus eupeus scorpion venom

Iranian scorpions belong mainly to the Buthidae and Scorpionidae families, distributed into 16 genera and 25 species. In Iran, similar to other parts of the world, there are a few known species of scorpions responsible for severe envenoming; amongst which Mesobuthus eupeus is the most common. Its venom contains several toxin fractions that may affect the ion channel. In the present study purifi...

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The Effects of Isolated Fractions of Mesobuthus eupeus Scorpion Venom on Humoral Immune Response

Background Many elements such as immunosuppressive, chemotactic and anti-inflammatory peptide that could effect on human and animals physiologic system were determined in venom. This study evaluated the use of Mesobuthus eupeus scorpion venom fractions as an immunomodulator. Methods The venom fractions collected from Khuzestan Province in South West of Iran were purified by ion exchange chrom...

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First transcriptome analysis of Iranian scorpion, Mesobuthus eupeus venom gland

Scorpions are generally an important source of bioactive components, including toxins and other small peptides as attractive molecules for new drug development. Mesobuthus eupeus, from medically important and widely distributed Buthidae family, is the most abundant species in Iran. Researchers are interesting on the gland of this scorpion due to the complexity of its venom. Here, we have analyz...

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Preparation and biodistribution study of a 99mTc-labeled toxic fraction of Iranian mesobuthus eupeus scorpion venom

  Introduction: Iranian scorpion species are classified in Buthidae and Scorpionidae with 16 genera and 25 species. In Iran, similar to other parts of the world, there are a few known species of scorpions responsible for severe envenoming. Mesobuthus eupeus is the most common species in Iran. Its venom contains several toxin fractions which can affect the ion...

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Oral Absorption of Mesobuthus eupeus Scorpion Venom in Mice

Background: To explore the oral absorption of scorpion venom an ELISA were designed in this study. Scorpions and their venom were been used for centuries as medical treatments in traditional medicine. The oral administration of drug referred as the convenient way, as there was not any publication about gastro-intestinal absorption of scorpion venom; this experiment checked oral absorption of Me...

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ژورنال

عنوان ژورنال: Journal of Venomous Animals and Toxins including Tropical Diseases

سال: 2010

ISSN: 1678-9199

DOI: 10.1590/s1678-91992010000400015