Compensatory Cell Movements Confer Robustness to Mechanical Deformation during Embryonic Development
نویسندگان
چکیده
منابع مشابه
Compensatory Cell Movements Confer Robustness to Mechanical Deformation during Embryonic Development.
Embryonic development must proceed despite both internal molecular fluctuations and external perturbations. However, mechanisms that provide robustness to mechanical perturbation remain largely uncharacterized. Here, we use light-sheet microscopy, comprehensive single-cell tracking, and targeted cell ablation to study the response of Caenorhabditis elegans embryos to external compression. Compr...
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miR-263a/b are members of a conserved family of microRNAs that are expressed in peripheral sense organs across the animal kingdom. Here we present evidence that miR-263a and miR-263b play a role in protecting Drosophila mechanosensory bristles from apoptosis by down-regulating the pro-apoptotic gene head involution defective. Both microRNAs are expressed in the bristle progenitors, and despite ...
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ژورنال
عنوان ژورنال: Cell Systems
سال: 2016
ISSN: 2405-4712
DOI: 10.1016/j.cels.2016.07.005