Complement activation-related pseudoallergy in dogs following intravenous administration of a liposomal formulation of meglumine antimoniate
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چکیده
منابع مشابه
Cardiopulmonary and hemodynamic changes in complement activation-related pseudoallergy
Complement activation-related pseudoallergy (CARPA) is a frequent side effect of intravenous therapies with nanoparticle-containing drugs and biologicals that are recognized by the immune system as foreign. It is an acute infusion reaction dominated by cutaneous and hemodynamic changes, most significantly a cardiopulmonary distress involving major pulmonary hypertension, systemic hypotension an...
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The toxicity and antileishmanial effectiveness of a novel liposome formulation of meglumine antimoniate in mongrel dogs with visceral leishmaniasis (VL) obtained from a region where VL is endemic in Brazil have been investigated. Groups of 12 animals received by the intravenous route four doses (with 4-day intervals) of either liposomal meglumine antimoniate (group I [GI], 6.5 mg Sb/kg of body ...
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ژورنال
عنوان ژورنال: Pesquisa Veterinária Brasileira
سال: 2013
ISSN: 0100-736X
DOI: 10.1590/s0100-736x2013000800012