Complement in nephritis.
نویسندگان
چکیده
منابع مشابه
Complement in Lupus Nephritis
The complement cascade consists of a series of plasma proteins that not only play a vital role in destroying pathogens but also mediate humoral and cellular interactions within the immune system (Figure). Recent work, driven particularly by the availability of gene-targeted mice, has considerably increased our understanding of the links between the complement system and glomerular disease. In t...
متن کاملComplement in Lupus Nephritis
The complement cascade consists of a series of plasma proteins that not only play a vital role in destroying pathogens but also mediate humoral and cellular interactions within the immune system (Figure). Recent work, driven particularly by the availability of gene-targeted mice, has considerably increased our understanding of the links between the complement system and glomerular disease. In t...
متن کاملThe Complement System in Lupus Nephritis.
The complement system is composed of a family of soluble and membrane-bound proteins that historically has been viewed as a key component of the innate immune system, with a primary role of providing a first-line defense against microorganisms. Although this role indeed is important, complement has many other physiological roles, including the following: (1) influencing appropriate immune respo...
متن کاملComplement in Lupus Nephritis: New Perspectives
Background: Systemic lupus erythematosus (SLE) is an autoimmune disorder caused by loss of tolerance to self-antigens, the production of autoantibodies and deposition of complement-fixing immune complexes (ICs) in injured tissues. SLE is characterized by a wide range of clinical manifestations and targeted organs, with lupus nephritis being one of the most serious complications. The complement ...
متن کاملComplement in Lupus Nephritis: New Perspectives.
BACKGROUND Systemic lupus erythematosus (SLE) is an autoimmune disorder caused by loss of tolerance to self-antigens, the production of autoantibodies and deposition of complement-fixing immune complexes (ICs) in injured tissues. SLE is characterized by a wide range of clinical manifestations and targeted organs, with lupus nephritis being one of the most serious complications. The complement s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 1973
ISSN: 0032-5473
DOI: 10.1136/pgmj.49.575.630