Complex View on Poisoning with Nerve Agents and Organophosphates
نویسندگان
چکیده
منابع مشابه
Laboratory Diagnosis of Organophosphates/Nerve Agent Poisoning
Organophosphorus inhibitors of cholinesterases (commonly called organophosphates, OP) are used in industry as softening agents, hydraulic liquids, lubricant additives, plasticizers, antioxidants, and for antiflammable modifications. They are also used in veterinary or human medicine as drugs or chemicals for the study of nervous functions. They differ in their toxicity from practically non-toxi...
متن کاملRecent Advances In Treatment of Acute Organophosphorous Nerve Agents Poisoning
Organophosphorous (OP) chemical warfare nerve agents mainly sarin and tabun were used during the Iran-Iraq war with high mortalities. In addition to atropine and oximes, the followings have recently been used successfully for the treatment of OP poisoning. 1. Sodium Bicarbonate: Infusion of high doses of sodium bicarbonate (5 mEq/kg in 60 min. followed by 5-6 mEq/kg/day to obtain arterial blood...
متن کاملRecent Advances In Treatment of Acute Organophosphorous Nerve Agents Poisoning
Organophosphorous (OP) chemical warfare nerve agents mainly sarin and tabun were used during the Iran-Iraq war with high mortalities. In addition to atropine and oximes, the followings have recently been used successfully for the treatment of OP poisoning. 1. Sodium Bicarbonate: Infusion of high doses of sodium bicarbonate (5 mEq/kg in 60 min. followed by 5-6 mEq/kg/day to obtain arterial blood...
متن کاملEffective countermeasure against poisoning by organophosphorus insecticides and nerve agents.
The nerve agents soman, sarin, VX, and tabun are deadly organophosphorus (OP) compounds chemically related to OP insecticides. Most of their acute toxicity results from the irreversible inhibition of acetylcholinesterase (AChE), the enzyme that inactivates the neurotransmitter acetylcholine. The limitations of available therapies against OP poisoning are well recognized, and more effective anti...
متن کاملA QSAR Approach to Physico-Chemical Data for Organophosphates with Special Focus on Known and Potential Nerve Agents
Internet Electronic Journal of Molecular Design 2004, xxxx Abstract Nerve agents like Sarin, Tabun, Soman, VX, Amiton etc are highly toxic organophosphates (OPs) that exert their toxic effect by inhibition of acetylcholine esterase. These compounds have received considerable interest due their inherent nature as weapons of mass destruction. Since these compounds have been developed for military...
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ژورنال
عنوان ژورنال: Acta Medica (Hradec Kralove, Czech Republic)
سال: 2005
ISSN: 1211-4286,1805-9694
DOI: 10.14712/18059694.2018.23