Component resolved diagnostics for hymenoptera venom allergy

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Component resolved diagnostics for hymenoptera venom allergy

PURPOSE OF REVIEW Component-resolved diagnostics makes use of defined allergen molecules to analyse IgE-mediated sensitizations at a molecular level. Here, we review recent studies on the use of component-resolved diagnostics in the field of Hymenoptera venom allergy (HVA) and discuss its benefits and limitations. RECENT FINDINGS Component resolution in HVA has moved from single molecules to ...

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Diagnostics in Hymenoptera venom allergy: current concepts and developments with special focus on molecular allergy diagnostics

BACKGROUND The high rate of asymptomatic sensitization to Hymenoptera venom, difficulty in correctly identifying Hymenoptera and loss of sensitization over time make an accurate diagnosis of Hymenoptera venom allergy challenging. Although routine diagnostic tests encompassing skin tests and the detection of venom-specific IgE antibodies with whole venom preparations are reliable, they offer ins...

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90 Improving the Diagnosis of Hymenoptera Venom Allergy: Component Resolved Diagnosis

relationship to proportion of regulatory T cells. Methods: Forty-five patients with history of systemic symptoms of allergy to Hymenoptera venom were included. Basophil reactivity before the treatment and after one year of allergen immunotherapy (AIT) was measured by CD63 expression, CD203c marker used for basophil identification. Cells were stimulated by aqueous solution of allergen in concent...

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Tryptase and Hymenoptera Venom Allergy

Antecedentes: La gravedad de la reacción tras una picadura de himenópteros se ha relacionado con la presencia de niveles elevados de triptasa sérica. El propósito del estudio fue cuantifi car los niveles basales de triptasa en pacientes con alergia al veneno de himenópteros e investigar la posible correlación entre estos niveles y la gravedad de la reacción a la picadura. Métodos: Participaron ...

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Diagnosis of Hymenoptera venom allergy.

The purpose of diagnostic procedure is to classify a sting reaction by history, identify the underlying pathogenetic mechanism, and identify the offending insect. Diagnosis of Hymenoptera venom allergy thus forms the basis for the treatment. In the central and northern Europe vespid (mainly Vespula spp.) and honeybee stings are the most prevalent, whereas in the Mediterranean area stings from P...

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ژورنال

عنوان ژورنال: Current Opinion in Allergy & Clinical Immunology

سال: 2017

ISSN: 1528-4050,1473-6322

DOI: 10.1097/aci.0000000000000390