Components of Broussonetia papyrifera (L.) Vent. I. Structures of two new isoprenylated flavonols and two chalcone derivatives.

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Cytotoxic Activity of Broussonetia Papyrifera(l.) Vent on Mcf-7, Hela and Hepg2 Cell Lines

Objective: Broussonetia papyrifera is widely used in Chinese traditional medicine. The current study was carried out to evaluate cytotoxic activity of methanolic extracts of leaf, bark and fruit on MCF-7, HeLa and HepG2 cell lines. Methods: The cytotoxic activity was determined as percentage of growth inhibition and cytotoxicity by Trypan blue dye exclusion assay and MTT assay respectively. Res...

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Overexpression of AtNHX5 improves tolerance to both salt and drought stress in Broussonetia papyrifera (L.) Vent.

Paper mulberry (Broussonetia papyrifera L. Vent) is well known for its bark fibers, which are used for making paper, cloth, rope, etc. It was found that, in addition to its well-documented role in the enhancement of plant salt tolerance, overexpression of the Na+/H+ antiporter (AtNHX5) gene in paper mulberry plants showed high drought tolerance. After exposure to water deficiency and salt stres...

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Fungicidal effect of prenylated flavonol, papyriflavonol A, isolated from Broussonetia papyrifera (L.) vent. against Candida albicans.

Papyriflavonol A (PapA), a prenylated flavonoid (5,7,3',4'-tetrahydroxy-6,5'-di-(r,r-dimethylallyl)-flavonol), was isolated from the root barks of Broussonetia papyriferra. Our previous study showed that PapA has a broad-spectrum antimicrobial activity against pathogenic bacteria and fungi. In this study, the mode of action of PapA against Candida albicans was investigated to evaluate PapA as a...

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ژورنال

عنوان ژورنال: Chemical and Pharmaceutical Bulletin

سال: 1985

ISSN: 0009-2363,1347-5223

DOI: 10.1248/cpb.33.3250