منابع مشابه
Composite Hydrogels for Bone Regeneration
Over the past few decades, bone related disorders have constantly increased. Among all pathological conditions, osteoporosis is one of the most common and often leads to bone fractures. This is a massive burden and it affects an estimated 3 million people only in the UK. Furthermore, as the population ages, numbers are due to increase. In this context, novel biomaterials for bone fracture regen...
متن کاملMineralization of hydrogels for bone regeneration.
Hydrogels are an important class of highly hydrated polymers that are widely investigated for potential use in soft tissue engineering. Generally, however, hydrogels lack the ability to mineralize, preventing the formation of chemical bonds with hard tissues such as bone. A recent trend in tissue engineering involves the development of hydrogels that possess the capacity to mineralize. The stra...
متن کاملFunctionalized d-form self-assembling peptide hydrogels for bone regeneration
Bone defects are very common in orthopedics, and there is great need to develop suitable bone grafts for transplantation in vivo. However, current bone grafts still encounter some limitations, including limited availability, immune rejection, poor osteoinduction and osteoconduction, poor biocompatibility and degradation properties, etc. Self-assembling peptide nanofiber scaffolds have emerged a...
متن کاملBiodegradable hydrogels for bone regeneration through growth factor release
For successful tissue regeneration, growth factors should be released over a long period of time at the site of action, but their in vivo half-life time is very short. The sustained release of growth factors could be achieved by taking advantage of biodegradable hydrogels prepared from acidic gelatin with an isoelectric point (IEP) of 5.0. When mixed with this negatively charged gelatin, positi...
متن کاملEffect of osteoconductive hyaluronate hydrogels on calvarial bone regeneration
BACKGROUND Without exploitation of possibly immunogenic and carcinogenic bone morphogenetic protein, we developed simple but clinically feasible artificial bone graft using osteoconductive hyaluronate (HA) hydrogels and bioactive MegaGen synthetic bone (MGSB). METHODS HA hydrogels were synthesized by the crosslinking reaction between carboxyl groups of HA and amine groups of gelatin (GEL). Th...
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ژورنال
عنوان ژورنال: Materials
سال: 2016
ISSN: 1996-1944
DOI: 10.3390/ma9040267