Comprehensive review of visual defects reported with topiramate

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چکیده

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Comprehensive review of visual defects reported with topiramate

OBJECTIVE The objective of this study was to analyze clinical patterns of visual field defects (VFDs) reported with topiramate treatment and assess possible mechanism of action (MOA) for antiepileptic drug (AED) associated VFDs. METHODS A comprehensive topiramate database review included preclinical data, sponsor's clinical trials database, postmarketing spontaneous reports, and medical liter...

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ژورنال

عنوان ژورنال: Clinical Ophthalmology

سال: 2017

ISSN: 1177-5483

DOI: 10.2147/opth.s125768