Computation of multilocus prior probability of autozygosity for complex inbred pedigrees
نویسندگان
چکیده
منابع مشابه
Computation of multilocus prior probability of autozygosity for complex inbred pedigrees.
Homozygosity mapping is a very powerful method for mapping rare recessive diseases in humans. In many applications, it is often desirable to compute prior (or unconditional) multilocus probability of autozygosity for inbred pedigrees. This paper proposes a simple yet powerful method for computing the prior multilocus autozygosity probability for complex inbred pedigrees. The method has an added...
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Conditional probability methods for haplotyping in pedigrees.
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ژورنال
عنوان ژورنال: Genetic Epidemiology
سال: 1997
ISSN: 0741-0395,1098-2272
DOI: 10.1002/(sici)1098-2272(1997)14:1<1::aid-gepi1>3.0.co;2-c