Computer programs for handling nucleic acid sequences
نویسندگان
چکیده
منابع مشابه
Computer analysis of nucleic acid sequences.
The increasing body of nucleic acid sequence data has created interest among many scientists in computational aspects of data storage and data processing. In fact GenBank and other data bases hade been created in order to store the data in a useful format, both for archival and analysis purposes. (See Burks et a/.' for a review of GenBank activities.) The value of simply have easy a m e s to al...
متن کاملNew approaches for computer analysis of nucleic acid sequences.
A new high-speed computer algorithm is outlined that ascertains within and between nucleic acid and protein sequences all direct repeats, dyad symmetries, and other structural relationships. Large repeats, repeats of high frequency, dyad symmetries of specified stem length and loop distance, and their distributions are determined. Significance of homologies is assessed by a hierarchy of permuta...
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This paper describes computer methods for locating signals in nucleic acid sequences. The signals include ribosome binding sites, promoter sequences and splice junctions. The methods are of use both to those trying to interpret the function of newly determined sequences and to those studying the molecular mechanisms involved in the recognition of these special signal sequences.
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Four computer programs are described which allow two amino acid or DNA sequences to be compared for homology, the results being displayed in a 2-dimensional array on a printer page. The programs also may be used to visualize repeated sequences or dyad symmetry within a DNA sequence. Two of the four programs may be used with any printer, the other two require a printer with graphics capability. ...
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Computer programs for the analysis of data from techniques frequently used in nucleic acids research are described. In addition to calculating non-linear, least-squares solutions to equations describing these systems, the programs allow for data editing, normalization, plotting and storage, and are flexible and simple to use. Typical applications of the programs are described.
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1984
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/12.1part1.379