Condensin and cohesin display different arm conformations with characteristic hinge angles
نویسندگان
چکیده
منابع مشابه
Taking cohesin and condensin in context
Structural maintenance of chromosome (SMC) protein complexes, including cohesin and condensin, are increasingly being recognized for their important role in cancer and development, making it critical that we understand how these evolutionarily conserved multi-subunit protein complexes associate with and organize the genome. We review adaptor proteins for SMC complexes and how these adaptors may...
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Condensin is a conserved five-subunit complex containing two SMC (structural maintenance of chromosomes) and three non-SMC subunits and plays a major role in mitotic chromosome condensation. Condensin also acts in interphase and is required for DNA repair and replication checkpoint control. We attempted to study the function of the condensin in greater detail by means of the isolation of intera...
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Cohesin and condensin complexes are essential for defining the topology of chromosomes through the cell cycle. Here we look at the emerging role of these complexes in regulating chromatin structure and gene expression and reflect on how these activities could be linked with chromosome topology.
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In this paper, we focus on 3D rotations on grid points computed by using only integers. For that purpose, we study the intersection between the 3D half-grid and the rotation plane. From this intersection, we define 3D hinge angles which determine a transit of a grid point from a voxel to its adjacent voxel during the rotation. Then, we give a method to sort all 3D hinge angles with integer comp...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2002
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.200111002