Configuration of electrical spinal cord stimulation through real-time processing of gait kinematics
نویسندگان
چکیده
منابع مشابه
Electrical stimulation in spinal cord injury.
The use of electricity to stimulate nerves or muscles is nothing new. In the 18th century Galvani recognized that electricity could be converted into "nerve force". Numerous applications of electrical stimulation have been explored, most notably cardiac pacing, cochlear implants or transcutaneous electrical nerve stimulation (TENS) units for pain control. Spinal cord injury (SCI), with its "tra...
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Locomotor behavior is controlled by specific neural circuits called central pattern generators primarily located at the lumbosacral spinal cord. These locomotor-related neuronal circuits have a high level of automaticity; that is, they can produce a "stepping" movement pattern also seen on electromyography (EMG) in the absence of supraspinal and/or peripheral afferent inputs. These circuits can...
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Stem Cells for Recovery of Human Central Nervous System Function. " In response to the Route 28 challenge, we propose a novel combinatorial treatment approach using multiple biological interventions in conjunction with controlled electrical stimulation to enhance the benefits of a cellular replacement strategy. Using an aligned polymer scaffold seeded with embryonic neural stem cells, we aim to...
متن کاملExcessive reflexes in spinal cord injury triggered by electrical stimulation.
Interaction of electrocutaneous stimulation with an impaired human motor control system may result in unstable reflex loops causing excessive spastic reactions. These contractions are usually excluded from analysis since the presence of spasm is one of the criteria commonly applied for discarding a contraction. They may, however, provide interesting information on the nature of spasticity. The ...
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Although L-dopa continues to be the gold standard for treating motor symptoms of Parkinson's disease (PD), it presents long-term complications. Deep brain stimulation is effective, but only a small percentage of idiopathic PD patients are eligible. Based on results in animal models and a handful of patients, dorsal column stimulation (DCS) has been proposed as a potential therapy for PD. To dat...
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ژورنال
عنوان ژورنال: Nature Protocols
سال: 2018
ISSN: 1754-2189,1750-2799
DOI: 10.1038/s41596-018-0030-9