Conformational transitions of poly(dA-dT).poly(dA-dT) in ethanolic solutions

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Conformational transitions of poly(dA-dT)poly(dA-dT) in ethanolic solutions.

Examination of circular dichroic and phosphorus nuclear magnetic resonance spectra showed that poly(dA-dT)-poly(dA-dT) exhibited an ethanol-induced transition to the A form in an Na+ containing medium like natural DNAs. A mere replacement of the Na+ by Cs+ counterions meant that the polynucleotide was with a little cooperativity transformed into a novel conformation displaying a deep negative b...

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ژورنال

عنوان ژورنال: Nucleic Acids Research

سال: 1982

ISSN: 0305-1048,1362-4962

DOI: 10.1093/nar/10.21.6969