Conjugating Methotrexate to magnetite (Fe3O4) nanoparticles via trichloro-s-triazine

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Conjugating Methotrexate to magnetite (Fe(3)O(4)) nanoparticles via trichloro-s-triazine.

Monodisperse Fe(3)O(4) nanoparticles (NPs) originally synthesized with a hydrophobic oleylamine capping ligand were made water soluble and conjugated to the anticancer drug Methotrexate (MTX) using a new chemistry based on the readily available linker trichloro-s-triazine (TsT). This new linker is much more versatile than those that currently exist for attaching biomolecules to magnetic NPs. Th...

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A new precursor for preparation of magnetite (Fe3O4) nanoparticles

An anionic Fe(II) complex, (BMIM)4[Fe(CN)6] (where BMIM is 1-butyl-3-methylimidazolium), was synthesized in ionic liquid [BMIM][PF6] under reflux condition. The complex was characterized by elemental analysis and spectroscopic methods. The magnetite (Fe3O4) nanoparticles were prepared by the hydrothermal and solvothermal (in ionic liquid [BMIM][PF6]) methods from (BMIM)4[Fe(CN)6] as a precursor...

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a new precursor for preparation of magnetite (fe3o4) nanoparticles

an anionic fe(ii) complex, (bmim)4[fe(cn)6] (where bmim is 1-butyl-3-methylimidazolium), was synthesized in ionic liquid [bmim][pf6] under reflux condition. the complex was characterized by elemental analysis and spectroscopic methods. the magnetite (fe3o4) nanoparticles were prepared by the hydrothermal and solvothermal (in ionic liquid [bmim][pf6]) methods from (bmim)4[fe(cn)6] as a precursor...

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ژورنال

عنوان ژورنال: Journal of Materials Chemistry

سال: 2009

ISSN: 0959-9428,1364-5501

DOI: 10.1039/b902373a