Consideration of Rat Chronic Progressive Nephropathy in Regulatory Evaluations for Carcinogenicity
نویسندگان
چکیده
منابع مشابه
Consideration of Rat Chronic Progressive Nephropathy in Regulatory Evaluations for Carcinogenicity
Chronic progressive nephropathy (CPN) is a spontaneous renal disease of rats which can be a serious confounder in toxicology studies. It is a progressive disease with known physiological factors that modify disease progression, such as high dietary protein. The weight of evidence supports an absence of a renal counterpart in humans. There is extensive evidence that advanced CPN, particularly en...
متن کاملassessment of the effect of honey as a topical therapy for intra oral wound healing in rat.
چکیده ندارد.
15 صفحه اولstudy of cohesive devices in the textbook of english for the students of apsychology by rastegarpour
this study investigates the cohesive devices used in the textbook of english for the students of psychology. the research questions and hypotheses in the present study are based on what frequency and distribution of grammatical and lexical cohesive devices are. then, to answer the questions all grammatical and lexical cohesive devices in reading comprehension passages from 6 units of 21units th...
Development of carcinogenicity classifications and evaluations: the case of formaldehyde.
In this paper carcinogenicity classification and evaluations case of formaldehyde made by national and international agencies and organizations (such as European Union, International Agency for Research on Cancer, World Health Organization) both in occupational (such as American Conference of Government Industrial Hygienists, National Institute of Occupational Safety and Health and Occupational...
متن کاملA two-year study with cimetidine in the rat: assessment for chronic toxicity and carcinogenicity.
A Two-Year Study with Cimetidine in the Rat: Assessment for Chronic Toxicity and Carcinogenicity. LESLIE, G. B., NOAKES, D. N., POLLITT, F. D., ROE, F. J. C., AND WALKER T. F. (1981). Toxicol. Appl. PharmacoL 61, 119-137. Cimetidine [Am-cyano-N-methyl-N1{2[(5-methylimidazol-4-yl)methylthio]ethyl}guanidine] was administered daily for 2 years by gavage to Wistar rats at dose levels of 950, 378, a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 2012
ISSN: 1096-6080,1096-0929
DOI: 10.1093/toxsci/kfs305