Contactless Bio‐Electrofunctionalization of Planar Micropores

Abstract The localized functionalization of pores and channels micrometric sub‐micrometric sizes is a bottleneck in surface chemistry. A method for the regioselective chemical planar presented, that are, restrictions microfluidic channels, here made SiO 2 ‐coated silicon. This strategy, based on bipolar electrochemistry, exploits combined presence constriction deoxidation pattern within pore affects electrical field distribution inside channel. It not only shown it capable regioselectively functionalizing at relatively small potential difference applied across it, but also possibility positioning area or edges depending design proved. These results are perfect correlation with numerical simulations electric micropores carried out using software Comsol Multiphysics. technique therefore very promising, particularly biosensors. specific DNA hybridization test has been successfully out, which represents first step toward bioanalytical health applications.