Contribution of genetic variation to transgenerational inheritance of DNA methylation
نویسندگان
چکیده
منابع مشابه
DNA methylation mediates genetic variation for adaptive transgenerational plasticity.
Environmental stresses experienced by individual parents can influence offspring phenotypes in ways that enhance survival under similar conditions. Although such adaptive transgenerational plasticity is well documented, its transmission mechanisms are generally unknown. One possible mechanism is environmentally induced DNA methylation changes. We tested this hypothesis in the annual plant Polyg...
متن کاملAssociation study between DNA methylation and genetic variation of APOE gene with the risk of coronary artery disease
Coronary artery disease (CAD) is a common health problem with a high rate of disability and death. Dyslipidemia and altered metabolism of Apo-lipoproteins are involved in the CAD pathogenesis. The current study investigated two common polymorphisms (rs429358 and rs7412) and promoter DNA methylation status of APOE in the Iranian CAD patients and control subjects. Two hundred angiographi...
متن کاملRole of genetic polymorphisms in transgenerational inheritance in budding yeast
We studied the effect of single nucleotide polymorphisms (SNPs) on transgenerational inheritance of yeast segregants that were derived from a cross between a laboratory strain and a wild strain of Saccharomyces cerevisiae. We compared segregants with high minor allele content (MAC) relative to those with less and found a more dramatic shortening of the lag phase length for the high MAC group in...
متن کاملInheritance of DNA Methylation in Plant Genome
Genomic DNA contains not only information of DNA sequence, but also epigenetic information that is the direct DNA modification by methylation (the addition of methyl group to the 5th carbon of pyrimidine ring of cytosine) and histone modifications (acetylation, methylation, etc). Epigenetic information is closely related to regulation of gene expression. If a methyl group is dislocated to posit...
متن کاملcontribution of setting to the study of characters and the main idea in e. brontes: wuthering heights and t. hardys: return of the native.
this thesis aims to adduce an unmitigated and comprehensive explication concerning the relationship of three significant elements of fiction: setting, chracter and theme. my research is basically placed on two outstanding novels of the 19th century: emily brontes wuthering heights and thomas hardys return of the native. my endeavour lies in studying the correlation among the three above-mention...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genome Biology
سال: 2014
ISSN: 1465-6906
DOI: 10.1186/gb-2014-15-5-r73