Correcting Systematic Inflation in Genetic Association Tests That Consider Interaction Effects
نویسندگان
چکیده
منابع مشابه
Correcting systematic inflation in genetic association tests that consider interaction effects: application to a genome-wide association study of posttraumatic stress disorder.
IMPORTANCE Genetic association studies of psychiatric outcomes often consider interactions with environmental exposures and, in particular, apply tests that jointly consider gene and gene-environment interaction effects for analysis. Using a genome-wide association study (GWAS) of posttraumatic stress disorder (PTSD), we report that heteroscedasticity (defined as variability in outcome that dif...
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ژورنال
عنوان ژورنال: JAMA Psychiatry
سال: 2014
ISSN: 2168-622X
DOI: 10.1001/jamapsychiatry.2014.1339