Correlation of Intraoperative Parathyroid Hormone Levels of Primary Hyperparathyroidism with Single Adenoma Volume and Weight: Can Optimal Criteria be Created to End The Surgery?

Objective: To study the relationship of intraoperative parathormone (PTH) decrease levels with solitary parathyroid adenoma (SPA) weight, diameter, and volume in patients primary hyperparathyroidism (PHPT). Method: Prospectively evaluation consecutive undergoing parathyroidectomy (PTx) diagnosis PHPT related to SPA. Perioperative biochemical parameters patients; volume, weight diameters were recorded. Intraoperative PTH drop percentages calculated. Adenoma diameter measured calculated using preoperativ ultrasound. was weighed intraoperatively by surgeon. Results: Forty-five underwent PTx for a SPA between October 2018 2019. There 9 men 36 women, mean age 51 ± 14.94 years. A positive correlation identified maximum resected glands (r = 0.613, p< 0.001; r 0.871, 0.001, respectively). preoperative levels, albeit weak one 0.334, p 0.025). No significant found ioPTH rate 0.088, 0.565). Conclusions: We have not been able establish criteria based on PA that would allow us make decisions ending reducing persistent cases.