Corticosteroids and endothelial dysfunction

Corticosteroids and Endothelial Dysfunction

Corticosteroids and endothelial dysfunction Assessment of endothelial-mediated relaxation in situ is rapidly becoming the standard gauge of individual susceptibility to future cardiovascular dysfunction (Hadi et al 2005). In this issue of Vascular Health and Risk Management, Turner and colleagues (2005), in a pilot investigation, have proposed the concept that endothelial dysfunction in patient...

Endothelial dysfunction and diabetes.

Endothelial dysfunction and hypertension.

Endothelial Dysfunction and Inflammation

[Endothelial dysfunction and atherosclerosis].

Mammalian endothelium acts as a mediator in arterial and venous relaxation and contraction. Endothelium-dependent relaxation is due to endothelial release of powerful, non-prostanoid vasodilatory substances. The best known of these is the endothelial factor EDRF identified as nitrous oxide (NO). It is the end result of the metabolism of L-arginine by the NO synthetase of endothelial cells. In a...