Cowpox virus infection in natural field voleMicrotus agrestispopulations: significant negative impacts on survival

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Cowpox virus infection in natural field vole Microtus agrestis populations: significant negative impacts on survival.

1. Cowpox virus is an endemic virus circulating in populations of wild rodents. It has been implicated as a potential cause of population cycles in field voles Microtus agrestis L., in Britain, owing to a delayed density-dependent pattern in prevalence, but its impact on field vole demographic parameters is unknown. This study tests the hypothesis that wild field voles infected with cowpox viru...

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Mitoxantrone, an FDA-approved therapeutic for the treatment of cancer and multiple sclerosis, was previously reported to exhibit antiviral activity against vaccinia virus. To determine whether this activity extends to other orthopoxviruses, mitoxantrone was tested against cowpox and monkeypox. Mitoxantrone demonstrated an EC(50) of 0.25 μM against cowpox and 0.8 μM against monkeypox. Intraperit...

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Cowpox Virus in Llama, Italy

Cowpox virus (CPXV) was isolated from skin lesions of a llama on a farm in Italy. Transmission electron microscopy showed brick-shaped particles consistent with orthopoxviruses. CPXV-antibodies were detected in llama and human serum samples; a CPXV isolate had a hemagglutinin sequence identical to CPXV-MonKre08/1-2-3 strains isolated from banded mongooses in Germany.

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The Natural History of Cowpox

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Clinicopathological findings in persistent corneal cowpox infection.

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ژورنال

عنوان ژورنال: Journal of Animal Ecology

سال: 2008

ISSN: 0021-8790,1365-2656

DOI: 10.1111/j.1365-2656.2007.01302.x