Curation of characterized glycoside hydrolases of Fungal origin
نویسندگان
چکیده
منابع مشابه
Curation of characterized glycoside hydrolases of Fungal origin
Fungi produce a wide range of extracellular enzymes to break down plant cell walls, which are composed mainly of cellulose, lignin and hemicellulose. Among them are the glycoside hydrolases (GH), the largest and most diverse family of enzymes active on these substrates. To facilitate research and development of enzymes for the conversion of cell-wall polysaccharides into fermentable sugars, we ...
متن کاملmycoCLAP, the database for characterized lignocellulose-active proteins of fungal origin: resource and text mining curation support
Enzymes active on components of lignocellulosic biomass are used for industrial applications ranging from food processing to biofuels production. These include a diverse array of glycoside hydrolases, carbohydrate esterases, polysaccharide lyases and oxidoreductases. Fungi are prolific producers of these enzymes, spurring fungal genome sequencing efforts to identify and catalogue the genes that...
متن کاملGlycoside Hydrolases across Environmental Microbial Communities
Across many environments microbial glycoside hydrolases support the enzymatic processing of carbohydrates, a critical function in many ecosystems. Little is known about how the microbial composition of a community and the potential for carbohydrate processing relate to each other. Here, using 1,934 metagenomic datasets, we linked changes in community composition to variation of potential for ca...
متن کاملREVIEW Glycoside Hydrolases: Catalytic Base/Nucleophile Diversity
Recent studies have shown that a number of glycoside hydrolase families do not follow the classical catalytic mechanisms, as they lack a typical catalytic base/ nucleophile. A variety of mechanisms are used to replace this function, including substrate-assisted catalysis, a network of several residues, and the use of non-carboxylate residues or exogenous nucleophiles. Removal of the catalytic b...
متن کاملBioprospecting metagenomics of decaying wood: mining for new glycoside hydrolases
BACKGROUND To efficiently deconstruct recalcitrant plant biomass to fermentable sugars in industrial processes, biocatalysts of higher performance and lower cost are required. The genetic diversity found in the metagenomes of natural microbial biomass decay communities may harbor such enzymes. Our goal was to discover and characterize new glycoside hydrolases (GHases) from microbial biomass dec...
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ژورنال
عنوان ژورنال: Database
سال: 2011
ISSN: 1758-0463
DOI: 10.1093/database/bar020