Current and emerging therapies for corneal neovascularization
نویسندگان
چکیده
منابع مشابه
Understanding current and emerging therapies for HNC
STATEMENT OF NEED/PROGRAM OVERVIEW Cancers that develop in and around the oral mucosa are collectively referred to as head and neck cancers (HNCs). Although the major risk factors (tobacco use and excessive alcohol use) and most prevalent population (persons older than 60 years) are well-known, a new patient demographic is emerging. A recently identified association between HNCs, particularly o...
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PURPOSE To determine the effectiveness of multigene-based anti-angiogenic gene therapies for experimental murine corneal neovascularization (corneal NV). METHODS Recombinant retroviral vectors encoding murine endostatin (mEndo), murine-soluble vascular endothelial growth factor receptor-2 (msFlk-1), or murine-soluble Tie2 (msTie2) were constructed and packaged in PT67 cells. Viral titers were...
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Choroidal neovascularization (CNV) is the main cause of visual impairment in highly myopic patients younger than 50 years of age. There are different treatments for myopic CNV (mCNV), with 5- to 10-year outcomes currently. Chorioretinal atrophy is still the most important determinant factor for visual outcome. The purpose of this study is to provide an overview of the current treatments for mCN...
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ژورنال
عنوان ژورنال: The Ocular Surface
سال: 2018
ISSN: 1542-0124
DOI: 10.1016/j.jtos.2018.06.004