Current knowledge on feline injection-site sarcoma treatment

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Current knowledge on feline injection-site sarcoma treatment

Feline injection-site sarcomas (FISS) are malignant skin tumours of mesenchymal origin, the treatment of which is a challenge for veterinary surgeons. The role of surgery, radiotherapy and chemotherapy in FISS treatment has been studied, and a correlation between "clean" surgical margins and disease-free survival has been shown. In addition, clean surgical margins are one of the most important ...

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Feline injection-site sarcoma: ABCD guidelines on prevention and management.

OVERVIEW In cats, the most serious of adverse effects following vaccination is the occurrence of invasive sarcomas (mostly fibrosarcomas): so-called 'feline injection-site sarcomas' (FISSs). These develop at sites of previous vaccination or injection. They have characteristics that are distinct from those of fibrosarcomas in other areas and behave more aggressively. The rate of metastasis range...

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Feline injection-site sarcoma: past, present and future perspectives.

Feline injection-site sarcomas (FISS) have been known since the early 1990s. After an initial correlation with rabies and feline leukaemia virus vaccination, subsequent studies have demonstrated that an abnormal reaction of feline tissues to chronic inflammation was mainly responsible for the disease. The low incidence of FISS in the population is explained by its multifactorial aetiology, sinc...

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Nanocrystalline silver dressing and subatmospheric pressure therapy following neoadjuvant radiation therapy and surgical excision of a feline injection site sarcoma.

UNLABELLED CLINICAL SUMMARY: This is the first clinical report of use of a combination of nanocrystalline silver and subatmospheric pressure therapy to treat a resistant wound infection, following tumour removal and radiation therapy, in a difficult-to-manage surgical site in a cat. PRACTICAL RELEVANCE The therapy was well tolerated and the authors suggest it is a valid treatment protocol for...

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Injection site-associated sarcoma in the cat: treatment recommendations and results to date.

PRACTICAL RELEVANCE Feline injection site-associated sarcomas (FISSs) have been the cause of much controversy and concern since they were first reported in the early 1990s. While not solely associated with vaccination, there are implications for vaccination sites and schedules and, while guidance has been published, this appears to be permeating only slowly through to general practice. CLINIC...

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ژورنال

عنوان ژورنال: Acta Veterinaria Scandinavica

سال: 2017

ISSN: 1751-0147

DOI: 10.1186/s13028-017-0315-y