Current Status, Challenges, and Prospects for the Biological Production of Vanillin

Vanillin has been widely used as a flavoring agent in the food industry and precursor medicine polymer industries. However, use of chemically synthesized vanillin is prohibited some other Additionally, harsh conditions toxic substrates lead to environmental challenges energy waste. With rapid development synthetic biology, biological production from renewable resources through microbial fermentation gained great attention owing its high selectivity environmentally friendly properties. Accordingly, this article will discuss biosynthesis technology aspects chassis cell types substrate types. The key enzymes involved metabolic pathways are also discussed. Then, we summarize improvements process increase reduce toxicity microorganisms, possible future directions for be outlined.