D-Loop Mutation G42A/G46A Decreases Actin Dynamics
نویسندگان
چکیده
منابع مشابه
Interdomain loop mutation Asp190Cys of the tetracycline efflux transporter TetA(B) decreases affinity for substrate.
TetA(B), the tetracycline efflux protein from Tn10, has 12 predicted α-helices that span the Escherichia coli cytoplasmic membrane (10) and is a member of the Major Facilitator Superfamily (4). TetA(B) and related tetracycline antiporters use the bacterial transmembrane proton motive force to export one metal-tetracycline complex in exchange for one H + (12), thereby reducing the intracellular ...
متن کاملSignaling to Actin Dynamics
Address correspondence to Laura Machesky, Department of Biochemistry, University of Birmingham, Birmingham B15 2TT, UK. Tel: 44-121414-2504. Fax: 44-121-414-3982. E-mail: [email protected] or [email protected] T HE actin cytoskeleton of a eukaryotic cell is central to locomotion, phagocytosis, contractility, shape changes, cytokinesis and maintenance of polarity. The mechanisms throug...
متن کاملMeasuring Actin Dynamics
The actin cytoskeleton is a highly dynamic system responsible for maintaining cell shape and rigidity. In endothelial cells, the actin cytoskeleton undergoes a remarkable reorganization in response to shear at the cell surface. This rearrangement likely occurs through regulation of cytoskeletal dynamics. This thesis presents a viable technology for the measurement of two fundamental dynamic pro...
متن کاملModeling actin dynamics.
Actin monomers assemble into filaments that structurally support cells as well as drive membrane protrusion for cell movement. Within cells, some actin structures are very dynamic and turn over rapidly, while others are very stable. Even purified actin filament dynamics are complex, and researchers have often turned to mathematical models in order to interpret data, test hypotheses, make predic...
متن کاملTelomeres Do D-Loop–T-Loop
has suggested that telomere-binding proteins provide these functions. Telomere-Binding Proteins. The binding proteins that mediate telomere function come in two flavors: double-stranded DNA-binding proteins and single-stranded DNA end–binding proteins. The best-characterized end-Rarely it seems does a new result emerge, loop around, binding protein is the ␣/ heterodimer protein from Oxy-and bi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biomolecules
سال: 2020
ISSN: 2218-273X
DOI: 10.3390/biom10050736