Database on pharmacophore analysis of active principles, from medicinal plants

Database on pharmacophore analysis of active principles, from medicinal plants

UNLABELLED Plants continue to be a major source of medicines, as they have been throughout human history. In the present days, drug discovery from plants involves a multidisciplinary approach combining ethnobotanical, phytochemical and biological techniques to provide us new chemical compounds (lead molecules) for the development of drugs against various pharmacological targets, including cance...

Medicinal Plants Database and Three Dimensional Structure of the Chemical Compounds from Medicinal Plants in Indonesia

During this era of new drug designing, medicinal plants had become a very interesting object of further research. Pharmacology screening of active compound of medicinal plants would be time consuming and costly. Molecular docking is one of the in silico method which is more efficient compare to in vitro or in vivo method for its capability of finding the active compound in medicinal plants. In ...

SHPIS: A Database of Medicinal Plants from Saudi Arabia

Many studies in the past have revealed the use of the indigenous medicinal plant for the treatment of various diseases in Saudi Arabia. However, the details of these indigenous essential medicinal herbs and their therapeutic implication against various human and animals diseases are not well documented and organised in a local platform. In this regard, a thorough mining of scholarly article for...

Pharmacophore modeling and in silico toxicity assessment of potential anticancer agents from African medicinal plants

Molecular modeling has been employed in the search for lead compounds of chemotherapy to fight cancer. In this study, pharmacophore models have been generated and validated for use in virtual screening protocols for eight known anticancer drug targets, including tyrosine kinase, protein kinase B β, cyclin-dependent kinase, protein farnesyltransferase, human protein kinase, glycogen synthase kin...

Identification of active principles from medicinal plants against Entamoeba histolytica Thesis submitted for the Degree of Doctor of Philosophy (Science)