DCs regulate TFH generation
نویسندگان
چکیده
منابع مشابه
Type II NKT-TFH cells against Gaucher lipids regulate B-cell immunity and inflammation.
Chronic inflammation including B-cell activation is commonly observed in both inherited (Gaucher disease [GD]) and acquired disorders of lipid metabolism. However, the cellular mechanisms underlying B-cell activation in these settings remain to be elucidated. Here, we report that β-glucosylceramide 22:0 (βGL1-22) and glucosylsphingosine (LGL1), 2 major sphingolipids accumulated in GD, can be re...
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ژورنال
عنوان ژورنال: Nature Immunology
سال: 2016
ISSN: 1529-2908,1529-2916
DOI: 10.1038/ni.3473