De-programming colorectal cancer by increase in cholesterol level
نویسندگان
چکیده
منابع مشابه
Investigating FGF11 gene transcription level in cancer cells among colorectal cancer patients
Background: Colorectal cancer (CRC) is the fourth leading cause of cancer-caused death around the world. Reports of the unnecessary transcription of family genes of the fibroblast growth factor in several types of cancer indicate the role of these factors in tumorgenesis and progression of cancer. Therefore, the level of FGF11 transcription was evaluated in colorectal cancer tumor tissues relat...
متن کاملIncrease in activity and level of pp60c-src in progressive stages of human colorectal cancer.
Activation of the tyrosine kinase of the c-src gene product, pp60c-src, has been shown to occur in nearly every primary colorectal carcinoma, and is found as early as in polyps of high malignant potential. However, no studies have addressed potential pp60c-src changes which occur during progression. To examine this question, we have studied kinase activity and protein levels in 7 colonic polyps...
متن کاملInvestigating the CTGF mRNA Expression Level in Patients with Colorectal Cancer
Background: The Connective Tissue Growth Factor (CTGF) gene encoding an extracellular matrix (ECM)-associated protein and as a member of the CCN family of proteins plays a major role in fibrosis, inflammation and connective tissue remodeling in a variety of diseases including cancer. The CCN proteins are multifunctional and are involved in cell proliferation, adhesion and cell development durin...
متن کاملdeprivation level and the risk of colorectal cancer by anatomic subsite in northern england
abstract: background: evidence suggests that the incidence of many cancers including bowel cancer vary according to socioeconomic status and education. in case of colorectal cancer, the direction of this association might be even different for anatomical subsites. the aim of this study was to describe the variation in the incidence of colorectal cancer by subsites across north of england and co...
متن کاملRole of Molecular Biomarkers in Colorectal Cancer
Colorectal cancer (CRC) is amongst the most widespread cancers and is a most common cause of cancer associated mortality universally. Since previous decades, it has been cleared that CRC develops owing to the buildup of a series of genetic and epigenetic changes in the normal colonic epithelium. Regardless of the current development in surgery and therapies, overall survival of end stage CRC pa...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cancer Reports and Reviews
سال: 2017
ISSN: 2513-9290
DOI: 10.15761/crr.1000125