Decellularization of donor pancreatic fragment to obtain a tissue-specific matrix scaffold

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Tooth tissue engineering: tooth decellularization for natural scaffold

AIM Tissue engineering is a multidisciplinary science that aims to produce replacement organs and biological substitutes. One of the techniques involves decellularizing a biological organ without altering its structure. One challenge is how to demonstrate which method would be better for this process. METHODOLOGY Fifty premolar teeth were divided into five groups: G1 (control): solution of 10...

متن کامل

Corneal Decellularization: A Method of Recycling Unsuitable Donor Tissue for Clinical Translation?

BACKGROUND There is a clinical need for biomimetic corneas that are as effective, preferably superior, to cadaveric donor tissue. Decellularized tissues are advantageous compared to synthetic or semi-synthetic engineered tissues in that the native matrix ultrastructure and intrinsic biological cues including growth factors, cytokines and glycosaminoglycans may be retained. However, there is cur...

متن کامل

A Tissue-Specific Scaffold for Tissue Engineering-Based Ureteral Reconstruction

Terminally differentiated somatic cells can rapidly change phenotypes when they are isolated from their native tissue and cultured in vitro. This problem may become a barrier to tissue engineering-based organ reconstruction, which utilizes somatic cells. The present study was designed to validate the feasibility of maintaining the urothelial cell phenotype in a tissue-specific ureteral scaffold...

متن کامل

A review of advances in pancreatic tissue engineering

Background: A common treatment for patients with type 1 diabetes in which pancreatic beta cells are destroyed by their own immune system attack, is insulin injection. Because this treatment is not able to maintain complete glucose homeostasis compared to the function of endogenous insulin secreted by the pancreas; in the field of pancreatic tissue engineering, various treatment strategies have ...

متن کامل

Light-emitting diode effects on combined decellularization of tracheae. A novel approach to obtain biological scaffolds.

PURPOSE To obtain a decellularized tracheal scaffold associating traditional approaches with the novel light-emitting diode (LED) proposal. METHODS This study was performed with New Zealand adult rabbits weighing 3.0 - 4.0 kg. Different protocols (22) were used combining physical (agitation and LED irradiation), chemical (SDS and Triton X-100 detergents), and enzymatic methods (DNase and RNas...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Russian Journal of Transplantology and Artificial Organs

سال: 2020

ISSN: 2412-6160,1995-1191

DOI: 10.15825/1995-1191-2020-1-123-133