Decreased mitochondrial OGG1 expression is linked to mitochondrial defects and delayed hepatoma cell growth
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چکیده
منابع مشابه
Decreased mitochondrial OGG1 expression is linked to mitochondrial defects and delayed hepatoma cell growth.
Many solid tumor cells exhibit mitochondrial respiratory impairment; however, the mechanisms of such impairment in cancer development remain unclear. Here, we demonstrate that SNU human hepatoma cells with declined mitochondrial respiratory activity showed decreased expression of mitochondrial 8-oxoguanine DNA glycosylase/lyase (mtOGG1), a mitochondrial DNA repair enzyme; similar results were o...
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ژورنال
عنوان ژورنال: Molecules and Cells
سال: 2013
ISSN: 1016-8478,0219-1032
DOI: 10.1007/s10059-013-2343-4